Cannon

Our SuperHeroes

The Unseen Warriors

In a world where strength is often measured in power and speed, our greatest heroes show resilience in ways most cannot see. They fight battles not on grand stages, but in everyday moments—against challenges that most will never face.

Every child affected by the LMBRD2 gene mutation is a true hero. Their daily lives are a battle, an adventure filled with challenges where every small progress is a victory, and every smile is a beacon of light.

They face the invisible, the unknown, with a strength beyond imagination. Behind their eyes lies an unbreakable determination, a resilience that commands admiration. They teach us to see the world differently, to cherish every moment, and to redefine what true courage really means.

AND HERE IS:

LMBRD2 ASSOCIATION

History of a SuperHero

Cannon is a happy, sweet, observant, and playful 4 year old boy who was born with a spontaneous genetic mutation on the LMBRD2 gene. This genetic condition has significantly impacted Cannon’s speech and motor development. His parent’s first noticed Cannon was missing key milestones around 6 months old when he was unable to sit up or roll over independently. They flagged these concerns to his pediatrician and were connected to a neurodevelopmental team who originally diagnosed Cannon with mixed type Cerebral Palsy due to low muscle tone in his trunk and core with spasticity in his legs. His MRI and EEG results came back as unremarkable, and no brain damage or seizures were discovered. His family was then introduced to a genetics team who ran a whole exome test that uncovered an extremely rare genetic mutation known as LMBRD2. His parents immediately enrolled Cannon into physical, occupational, and speech therapy. They feel that early intervention has been integral to his key for his development. Cannon is now crawling, walking with assistance, attending preschool, and is beginning to communicate verbally. Overall, Cannon is in great health and continues to make slow but steady progress with motor and speech goals. His favorite things to do are play with other kids, swing, ride his tricycle, read books, dance, and spend time with his family. Cannon is the hardest working person we know and has been an incredible blessing to our family. We are grateful for our LMBRD2 community and are committed to further research on this condition. Cannon’s story is unique and we are excited to share it with the world.

And we do have many other all over the world.

Our heroes don’t wear capes, but they have wings—the wings of love, hope, and perseverance. Through them, we learn an essential truth: the greatest battles are not fought with weapons but with the heart.

We are proud to stand by them, to share their stories, and to make their voices heard. Because every child here is a symbol of strength, a spark of hope, a hero in their own right.